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ea0029p1415 | Pituitary Clinical | ICEECE2012

The effect of GH replacement therapy on exercise capacity, fat mass, ectopic lipids intramyocellular and intrahepatocellular lipids and insulin resistance in hypopituitary patients with GH deficiency

Egger A , Allemann S , Stettler C , Diem P , Buehler T , Boesch C , Christ E

Introduction: Increased levels of ectopic lipids (IMCL and IHCL) have been related to insulin resistance. Aerobic exercise affects IMCL. GHRT is known to increase exercise capacity, insulin resistance and decrease fat mass. The effect of GHRT on ectopic lipids is not known.Methods: Ten patients with GHD and ten sedentary control subjects (CS; matched for gender, age, BMI and waist) were recruited. VO2max was assessed using an exercise test on ...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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